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The patient self-administered various medications, including spiramycin tablets, Sanjie tablets, amoxicillin capsules, and Xiaoyao pills, to treat the symptoms, but with no relief, and in contrast the area of redness and local pain increased

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Disruptions in the intrinsic factor (IF) pathway, including impaired IF production due to autoimmune conditions (pernicious anemia), damage to the ileum from diseases like Crohns or celiac disease, or surgical resection of the ileum, can severely impair B12 absorption

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