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Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease

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When researchers used compound C (an AMPK inhibitor), the anti-osteoclast effects of MOTS-c were partially abolished, confirming the AMPK pathway as the key mechanism

These ulcers exemplify the combined effect of oxidative stress and chronic inflammation, where inflammation and ROS together create a feedback loop that exacerbates immune dysfunction and worsens neuropathy, complicating patient care [42,46]
