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For IHC, the sections were incubated with anti-CAPZA1 (1:200) or anti-SIRT6 (1:200) antibodies overnight, followed by incubation with HRP-polymer secondary antibodies and DAB substrate

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doi:10.1002/9780470132463.ch26

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These associations were also robust to different methods and evident for acetyl-carnitine

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Furthermore, individual differences in metabolic regulation may also affect the effectiveness of targeted therapies, such as in obese patients, where enhanced lipid metabolism makes them more prone to resistance (210)

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