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Resistance to avermectins: extent, mechanisms, and management implications

10.1093/toxsci/kfu002 116 NickensK

Nrf2 is inhibited by Kelch-like ECH-associated protein 1 (Keap1): specifically, it increases Nrf2 proteasome-mediated degradation [20,21]

Using the established fluorescent reporter myo-3 p::Queen-2m to monitor ATP levels in the body wall muscle 32 , we detected a mild ~6% decline in ATP levels after 24 h of fasting, a level that recovered upon refeeding (Supplementary Fig

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
