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In a recent study, LuzScheffer and Latini showed that regular PE with light / moderate intensity causes an anti-inflammatory response by stimulating the production of IL-6 and neopterin that subtly reduce the risk of infection and chronic non-communicable diseases and generate neuroprotection [149]
They also decrease the release of IL-33 through which inflammatory Th2 are reduced and IL-5 and 13 are released, leading to a reduced number of eosinophils and reduced goblet metaplasia and mucus production (Figure 2) [53]
