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doi: 10.1007/s00011-017-1079-6

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47 : 23952400 Paradies G, Ruggiero FM, Gadaleta MN, Quagliariello E

Ultimately, TMAO is distributed throughout the body, being eliminated via the kidneys or accumulating in tissues (47)

Inhibition of PCSK9 using siRNA, gene knockout, or anti-PCSK9 vaccination and antibodies promotes apoptosis in several cancer models in vitro, including human neuroglioma (Piao et al., 2015), lung adenocarcinoma (Xu et al., 2017), and pancreatic neuroendocrine neoplasms (Bai et al., 2017)