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Description

Another pathway for glucose oxidation, in addition to glycolysis and TCA, is the pentose phosphate pathway (PPP)

TGF- is an important regulator of neovascularization in tumor and it acts in a context-dependent manner by promoting angiogenesis via stimulation of pro-angiogenic factors like VEGF or inhibiting tumor angiogenesis by impairing endothelial cell proliferation and migration or by inducing apoptosis [211]

H.ArtsI

Subsequently, intracellular divalent metal transporter 1 (DMT1) and zinc transporter 8/14 (ZIP8/14) facilitate the storage of Fe2+ in the intracellular labile iron pool (LIP) (Sterling et al., 2017)