glutathione iv indications push What are the indications and

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[DOI] [PMC free article] [PubMed] [Google Scholar] 328.Levin J., Schmidt F., Boehm C., Prix C., Botzel K., Ryazanov S., Leonov A., Griesinger C., Giese A

[DOI] [PubMed] [Google Scholar] 55.Yao J.K., Leonard S., Reddy R

It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)

Excessive oxidative stress resulting from impaired antioxidant defenses is associated with increased health risks in humans 54