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Striatal and SNcVTA TH, SST, NPY expression and cell count data from each stage were analysed for statistical significance by two-tailed unpaired Students t -test

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10.1002/adma.201801362 73

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Protective effects of hericium erinaceus mycelium and its isolated erinacine A against Ischemia-Injury-Induced neuronal cell death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine

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A principal obstacle to successful CNS therapy is the highly selective BBB, which restricts the passage of nearly 98% low-MW compounds and effectively excludes most macromolecular agents from accessing the brain parenchyma (14)

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