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The relative lack of sebum in children and the decrease in the sebaceous gland secretion with advancing age may explain its rarity in pediatric age group and postmenopausal age group, respectively
Fat accumulation in Caenorhabditis elegans is mediated by SREBP homolog SBP-1
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Therefore, export and retention signals are mechanisms that regulate that only adequately folded and assembled receptor complexes are exported to the PM
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