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Dietary antioxidants as modifiers of physiologic adaptations to exercise

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(Clin Transl Med, 2021) in 24 older adults (aged 61-80) found that supplementation with GlyNAC (glycine 100 mg/kg/day + NAC 100 mg/kg/day, approximately 7 g each for a 70 kg person) for 16 weeks corrected glutathione deficiency and improved multiple hallmarks of aging including oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, body composition, exercise capacity, and cognition [10]

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In the REDEFINE 1 phase III trial, participants lost over 20% of body weight on average over 68 weeks using the CagriSema combination (cagrilintide plus semaglutide)