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Without human trials, every approach is an estimate
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Remember this crucial conversion: 1mg = 1000mcg So, our 10mg/mL solution is also a 10,000mcg/mL solution
In contrast, there is strong genetic and functional evidence that RAS-MAPK activation by canonical agonists or oncogenic RAS mutations is a key collaborator of TGF--activated SMADs in the induction of EMTs (see below)
