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In: Seminars in reproductive medicine

Conclusion In this study, we have identified a ~0.187% level of drug-tolerant persister cells with the CRC cell lines response to anticancer drugs, and we determined that there were G0/G1 cell cycle arrest, and upregulation of stemness factors and mesenchymal-like gene expression in the DTP cells

Mol Cell Endocrinol 12 : 267272

Alternative routes of administration include oral formulations, transdermal systems (gels and patches), and subcutaneous implants, which allow for more stable serum testosterone concentrations and individualized dosing strategies

Although this study was not randomized, it was found that amifostine was associated with protection from serious hearing loss (defined as hearing loss requiring a hearing aid or deafness)