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Results Initial studies identified dose-dependent bioavailability, with greater than proportional increases in exposure as dose increased resulting in a ~ twofold increase in bioavailability between the lowest and highest investigated doses

Gpr132 sensing of lactate mediates tumormacrophage interplay to promote breast cancer metastasis

The corresponding energy deficiencies due to mitochondrial dysfunction amplify oxidative stress via the release of more oxygen radicals into the CNS [204]

Encouraged by these structural and evolutionary parallels, researchers began exploring whether plant GLRs exhibit functional responses comparable to those in animals