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Importantly, thus far, no negative implications on cardiovascular or lung functions have been reported, although the long-term effects of chronic levodopa exposure to pulmonary mucosa and development of dyskinesia are unknown

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Lamas GA, Goertz C, Boineau R, Mark DB, Rozema T, Nahin RL, et al

Federal regulations (45 CFR 46 Subpart B) provide additional protections for pregnant women and neonates, and IRB review cannot approve protocols that expose infants to unknown developmental risks without compelling scientific justification and robust preclinical safety data

This study discovered that intraperitoneal administration of NAC significantly alleviated phosgene-induced pulmonary edema, as confirmed by decreased lung wet to dry weight ratio and oxidative stress markers