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Use of mass spectrometry techniques for the characterization of metal bound to proteins (metallomics) in biological systems
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1.2.3 LOAD subtypes and atypical variants Typical Amnestic AD: The classic presentation involves prominent memory loss due to early involvement of the hippocampus and medial temporal lobe structures (Ramanan et al., 2020)
Concurrently, NCOA4 mediates the autophagy of ferritin, releasing stored iron and further increasing free iron levels within cells ( Targeting these mechanisms by inhibiting the activity of hepcidin and NCOA4 offers new therapeutic avenues for OA
