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Description
Mechanism-based treatments Mechanism-based treatments aim to target the underlying pathophysiological processes of DN to alleviate symptoms and prevent disease progression
Needle Size: Use a 1 to 1.5-inch needle, 22-25 gauge for deep muscle penetration
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The most mechanistically coherent pairing is MOTS-c with resistance training and aerobic exercise
Dosing tiers: The 1.5 mg every-other-day protocol mirrors the approved Zadaxin regimen
