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Pharmacol Rev 57(2):27988 Kawamata Y et al (2003) A G protein-coupled receptor responsive to bile acids

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In this regard, as discussed above, it is important to note that subsequent work from our group demonstrated that at least some of the reported discrepancies relate to variability in the specific activity of commercially available recombinant GDF11 protein and to critical differences in experimental design [74,78] , and additional follow up studies from our labs [78] as well as studies from independent research groups [82,91-93] , have confirmed the reproducibility of our published results

Therefore, oral B12 supplements can be taken with or without food with minimal impact on absorption