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Age- As we age, our bodies may become less efficient at absorbing B12 from food, increasing the risk of deficiency

Its primary job is to combat oxidative stress by neutralizing free radicalsthose unstable molecules that damage cells, proteins, and DNA, contributing to aging and disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 279.Zarate YA, Hopkin RJ

CrossRef Synergistic effects of nicotine and hyperlipidemia induce cardiac damage via dynamic cardiomyocyte-based biosensing Cheng-Wen He, Xiaohuan Guo, Tao Liang, Pan Chen, Kaiqiang Li, Aibo Xu, Ke Hao, Ning Hu, Zhen Wang Microsystems & Nanoengineering.2026;[Epub] CrossRef Different Associations between Lipid Levels and Risk for Heart Failure according to Diabetes Progression Seung-Hwan Lee, Kyu Na Lee, Jong-Chan Youn, Hun Sung Kim, Kyungdo Han, Mee Kyoung Kim Diabetes & Metabolism Journal.2025

Furthermore, ABCC5 overexpression increased SLC7A11 expression, decreased lipid peroxidation, and increased intracellular GSH levels, resulting in reduced ferroptosis (91)