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1123 However, the aforementioned studies were primarily conducted in mouse models, and the clinical outcomes have been consistently unsatisfactory

6i), indicating that the thioredoxin system is unlikely a major contributor regulating ROS clearance in AIF3 splicing cells

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Exposure to these factors leads to the formation of free radicalschemical compounds containing unpaired electrons that can easily react with chemical substances and cause tissue damage if they appear in excess [1]
