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Cognitive and psychological problems such as memory loss, confusion, irritability, or depression appear after prolonged deficiency of vitamin B12

Sox5 And Sox6 Are Required For Notochord Extracellular Matrix Sheath Formation, Notochord Cell Survival And Development Of The Nucleus Pulposus Of Intervertebral Discs

Yes, if given by trained clinicians in an appropriate setting

A serum B12 level test and ideally a methylmalonic acid test should be performed before starting B12 injections
