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Elderly patients tend to have a greater frequency of decreased hepatic, renal, or cardiac function, and also have concomitant disease or receiving other drug therapy

BSH Guidelines for the diagnosis and treatment of cobalamin and folate disorders: Treatment of established cobalamin deciency should follow the schedules in the BNF (Grade 1A)

But B12 supplements don't seem to have any effect on people already at normal levels

Indeed, the expression of CD38 is elevated in multiple tissues and cell types during aging, which is largely attributable to its induction by SASP 11,27

It depends on the insurance and the patients condition