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Of the SCD patients, 16 of 17 were free of the vaso-occlusive crises that characterize the illness following treatment
Finally, the binding affinity ( K D ) of ES2 for FOXO4 and TP53 are 0.660 0.006 nM and 2.3 0.018 nM, respectively, revealing that FOXO4 binds ES2 with approximately 4-fold higher affinity compared to TP53
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