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"When I started puberty in fifth grade, that's when I started gaining a lot of weight," Demi said

However, seek urgent medical attention if you develop severe abdominal pain, persistent vomiting preventing fluid intake, signs of pancreatitis (severe upper abdominal pain radiating to the back), gallbladder problems (severe right upper quadrant pain, fever, or jaundice), or signs of allergic reaction (rash, facial swelling, or breathing difficulties)

Appropriate dosing and administration timing are critical determinants of tirzepatide effectiveness
Every 2.5mg increment is held for 4 weeks before advancing, giving the GI system time to adapt and minimizing the nausea, vomiting, and constipation that rushing produces
