glp 1 venom Gila monster venom… and weight loss? 🦎 It sounds wild, but it's true. GLP-1 medications were inspired by a hormone first discovered in the saliva of a Gila monster. On this week's is glp-1 made from venom

And society wouldnt have the GLP-1s, direct-acting antivirals, PCSK9 inhibitors, and countless other medicines we enjoy today many of which have already had their patents expire

Researchers discovered that the bodys natural GLP-1 system activates specific brain cells called GABA neurons (gamma-aminobutyric acid) in a region called the ventral tegmental area, or VTA

Today, there is still a large number of GLP-1R agonists entering clinical trials, which will lead to a big explosion in the future, so let's wait and see together

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes (FOCUS)

The two types of incretin hormones that have critical roles in incretin signaling, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), bind to specific members of the G-protein-coupled receptor (GPCR) family: the GLP-1 receptor (GLP-1R) and the GIP receptor (GIPR), respectively