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Nausea, vomiting, and gastrointestinal discomfort are well-documented side effects of licensed medicines such as semaglutide (the Wegovy injection and the newer oral Wegovy pill), liraglutide (Saxenda), orlistat, and naltrexone/bupropion (Mysimba)

doi: 10.1016/j.tice.2015.12.003 163 GebremedhnSSalilew-WondimDHoelkerMRingsFNeuhoffCTholenEet al

While standard prescribing typically follows weekly injections, many patients and providers explore alternative dosing schedules like every-other-week administration to optimize long-term adherence and sustainability

However: If you are unsure how long it sat out If temperatures were high If the pen was exposed to heat (cars, bags, sunlight, travel) Its safest to replace it

doi: 10.1073/pnas.85.10.3638