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Compared with DPP-4 inhibitors, the lower rate of hyperkalemia was consistently observed across individual agents in the SGLT-2 inhibitor (canagliflozin, dapagliflozin, empagliflozin) and GLP-1 receptor agonist (dulaglutide, exenatide, liraglutide, semaglutide) classes

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In vitro, the protein levels of IL-1 and TNF- in lipopolysaccharide-stimulated BV-2 microglia were also decreased by liraglutide

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