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Specifically, inhibiting or depleting spinal microglia abolished the anti-allodynic effects of morroniside, while neutralizing IL-10 or -endorphin with targeted antibodies, or blocking the -opioid receptor, fully reversed morroniside-induced mechanical anti-allodynia [74]

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[DOI] [PubMed] [Google Scholar] 11.Faillie JL, Yin H, Yu OH, Herrero A, Altwegg R, Renoux C, et al

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