does semaglutide have long term effects FDA Approves Oral as the First Oral GLP-1 Pill? Is Ozempic Safe for Long-Term

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In subjects with BMI 30 kg/m 2 , but without T2D, a phase 1 single ascending dose (SAD) trial shows that GL0034 at doses of 1,520 mcg, 2,000 mcg, and 2,520 mcg results in mean weight loss of 2.1%, 1.9%, and 2.5%, respectively, versus 0.3% weight gain for the placebo group one week after administration (42)

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But while the pill is now mainstream enough that the broader conversation has quieted (just wait until the male contraceptive pill clears clinical trials), GLP-1 drugs continue to make news nearly every day