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First, erythritol was patented for use as an agricultural insecticide and like any insecticide, it raises questions about its effects on gut flora and microbial communities

Kardie Tobb, DO, MS, FASPC, FACC, a boardcertified preventive cardiologist and the medical director for the Cone Health HeartCare Womens Heart Health and Cardio-Obstetrics Clinic, explains some of the most common reasons why GLP-1s may not deliver the results youre hoping for, including: You need a higher dose and have not yet reached a therapeutic dose as determined by your doctor High intake of liquid calories , including alcohol and ultra-processed foods Not getting enough protein , which can leave you persistently hungry and makes it harder to feel full Advanced diabetes or insulin resistance Taking other medications such as sulfonylureas, which lower blood sugar but can lead to weight gain Not adhering to your dosing schedule , such as inconsistent weekly injections or missed doses Differences in gut hormones or genetics And just because your GLP-1 isnt working immediately doesnt mean it wont work for you

I get this question every week, and it matters because these are not all the same drug

Age and sex The BP-lowering effects of GLP-1 RAs appear to be largely consistent across age- and sex-defined subpopulations

Thats where medical weight loss comes in