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Clinical trial population adjacent: Obese individuals with higher adiposity, MASLD, T2D/high HbA1c, and/or significant liver fat and metabolic panel improvement goals

Although some studies suggest gastroparesis is more common in type 2 diabetes, the USA-funded National Institutes of Health Gastroparesis Clinical Research Consortium reported a comparable prevalence, especially in longstanding and poorly controlled diabetes

Bone loss associated with rapid weight loss often does not fully reverse even after weight stabilizes

Analyses were performed from a third-party payer and healthcare sector perspectives

Thyroid imbalances, cortisol elevation, insulin resistance, vitamin deficiencies, and gastrointestinal inflammation can all influence how quickly the body responds to GLP 1 therapy