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Ashruf O, Mushtaq A, Lin C-T, Volk M, Orozco Z, Hundal J, Safdar A, Thompson C, Karimi S, Jain AG, Sukumar JS, Moudgil R, Mukherjee S, Schwartz GK, Kaelber D, Ma W, Adjei AA, Mustafa Ali MK, Singh A

Acronyms A1C - Hemoglobin A1C ADA - American Diabetes Association CVD - Cardiovascular disease DM - Diabetes mellitus FBS - Fasting blood sugar GFR - Glomerular filtration rate GI - Gastrointestinal GLP-1 - Glucagon-like peptide-1 OSA - Obstructive sleep apnea RCT - Randomized controlled trial T2DM - Type 2 diabetes mellitus Thyroid C-cell tumor = Thyroid medullary tumor DRUGS IN CLASS Dual GLP-1 and GIP agonists Tirzepatide (Mounjaro) - marketed for diabetes Tirzepatide (Zepbound) - marketed for weight loss MECHANISM OF ACTION GLP-1 and GIP GLP-1 stands for "glucagon-like peptide-1," and GIP stands for "glucose-dependent insulinotropic polypeptide." GIP is also sometimes referred to as "gastric inhibitory polypeptide." GLP-1 and GIP are hormones secreted by specialized cells in the small intestine in response to food consumption

It is a synthetic 39-amino acid peptide that acts as an agonist at both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R), producing synergistic metabolic effects that exceed those of selective GLP-1 agonists in clinical trials

You will get practical checks and simple steps to keep your treatment smooth, safe, and worry-free so you can use tirzepatide confidently without uncomfortable rashes

Expect a period of adjustment