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30 Additionally, GLP-1 and exendin-4 restored femur and vertebrae bone mass in hyperlipidaemic and hypercaloric Wistar rats

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Only your healthcare team can decide which of these drugs, if any, will work best for you

Metformin reduces hepatic glucose production, decreases intestinal glucose absorption, and increases peripheral insulin sensitivity, and may reduce appetite by raising glucagon like peptide-1 levels
There is no direct dose equivalence between the two compounds because they work through different receptor profiles
