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The most common side effectsnausea, vomiting, and gastrointestinal discomfortoccur in 2040% of users, whereas headache reports fall significantly lower

2020;8(4): e00621

So if you keep the body fat down, leptin stays down, and it seems to be regulating these other processes pretty well

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Jean-Pierre Raufman, M.D., Baltimore VA Medical Center (formerly with State University of New York Health Science Center) Selected publications: Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom