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This phased approach mirrors the regimen used in major weight loss trials and significantly reduces nausea rates compared to faster escalations

I would rather someone spend an extra two weeks at a lower dose feeling completely fine than rush up and spend a week feeling queasy

This is when the discipline challenge intensifies, because the pharmacological support is disappearing while the behavioral habits may not be fully cemented

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[1] [3] Importantly, patients should seek urgent medical attention if they experience severe or persistent abdominal pain (especially if radiating to the back), repeated vomiting, inability to keep fluids down, signs of dehydration, or jaundice, as these may indicate serious conditions such as pancreatitis or gallbladder disease