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I have a meal plan and everything. This was not the first time, nor the last, that I would be struck by a patient or providers characterization of weight loss as a matter of willpower and, at the same time, the powerful motivation and self-efficacy that can drive patients to take ownership of managing their chronic diseases

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Results Liraglutide and GUB09-145 improve metabolic parameters in DIO mice Following 35 weeks of feeding, DIO mice showed significantly increased body weight (53.0 0.6 g, n = 45) compared to chow controls (32.1 0.2 g, n = 10, p 0.05) following treatment with vehicle, liraglutide or GUB09-145 as compared to baseline (Fig