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Conclusion Escalating the dose of oral semaglutide to 14 mg could be an effective approach for enhancing glycemic control and managing body weight in individuals with type 2 diabetes.

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Effective therapies, such as insulin and Glucagon-like peptide-1 (GLP-1), require injections, which are costly and result in less patient compliance

To unlock wider and more equitable access to novel obesity treatments, however, positive cardiovascular outcomes data will be absolutely critical to demonstrate substantial cost-savings for health systems from medication-assisted weight loss by avoiding downstream complications from obesity-related comorbidities