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Weeks 5 to 8: Fine-tune

Funding This work was supported by the National Natural Science Foundation for Youths (Grant Nos

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Ma H., Huang W., Wang X., Zhao L., Jiang Y., Liu F., Guo W., Sun X., Zhong W., Yuan D., et al

In addition, it attenuates the nuclear translocation of NFATc1, a crucial downstream effector of the RANKL signaling pathway that is indispensable for the terminal stage of osteoclast differentiation (Mabilleau et al., 2016)
Then came Wegovy, a high-dose version officially marketed as an obesity treatment