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The search included terms such as small molecule GLP-1 receptor agonists, oral GLP-1 receptor agonists, Danuglipron, Orforglipron, and Aleniglipron. Additionally, information on ongoing clinical trials involving small molecule GLP-1 receptor agonists was retrieved from the ClinicalTrials.gov database using the same keywords
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31 However, a causal relationship has not been established
it has a half-life of 11 minutes and requires 3 injections per day
As a result, GLP-1-RA may possess anti-inflammatory properties that extend beyond glucose and weight control
