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March 25, 2024

Mean eGFR was 90.6 mL/min/1.73 m2 (SD 19.3) and median UACR was 14.6 mg/g [IQR 0.054.7]

Patients diagnosed with diabetes are initiating GLP-1 treatment more quickly than ever before Since 2021, the average time between a diabetes diagnosis and the initiation of a GLP-1 therapy has decreased by about one month, underscoring how quickly these drugs have moved to the forefront of care

reduced form)-dependent buffering systems, several constraint-sensitive metabolic processesincluding NAD partitioning, amino aciddependent antioxidantanabolic coupling, micronutrient-dependent enzymatic activity, and bile acidmediated absorptionmay become functionally limiting

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