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Food and Drug Administration (FDA) for the treatment of type 2 diabetes, and it has shown promising results in controlling blood sugar levels and promoting weight loss

GLP-1 helps control blood sugar by improving insulin sensitivity and reducing appetite, GIP helps insulin secretion and fat metabolism

These drugs are indicated for patients who are treated with intermediate or long-acting GS taken twice a day or more [20,21]

Administration of LPS, an endotoxin derived from Gram-negative bacteria that activates innate immunity and increases proinflammatory cytokines such as TNF-, IL-6, and IL-1, elevates circulating GLP-1 within 3 hours in mice and humans (57)

It was FDA-approved for type 2 diabetes management in 2005