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2025;17:e88334
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Tirzepatide might have a beneficial impact on many of these pathophysiological mechanisms (Fig
The mechanism involves the suppression of pro-inflammatory chemokine (C-C motif) ligand 20 (CCL20), which is of significant importance in the Th17 immune response, as well as IL-33, which is a key cytokine associated with Th2 immune responses [224]
Another concern involves medication adherence
