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Dose selection between 10 mg and 15 mg depends on individual factors including gastrointestinal tolerance, metabolic response, weight loss trajectory, and patient-reported side effects

Quarta C, Clemmensen C, Zhu Z, et al

Is it normal to not lose weight the first few weeks

The oral vs injection comparison explores the bioavailability differences and what oral dosing at equivalent efficacy levels might look like

"Lilly's triple agonist, retatrutide, delivered weight loss of up to an average of 71.2 lbs along with substantial relief from osteoarthritis pain in first successful Phase 3 trial." Eli Lilly and Company , 11 Dec