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Its receptor binding profile shows that it binds to GIP receptors with an affinity similar to the natural hormone but has a fivefold lower affinity for GLP-1 receptors

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On examination, he has a body mass index (calculated as weight in kilograms divided by height in meters squared) of 40, a blood pressure of 144/86 mm/Hg, and well-demarcated red, scaly plaques on the extensor surfaces of the arms, legs, trunk, and scalp, involving 25% of the body surface area

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