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If GI symptoms are still significant, the documented approach is to hold the current dose longer rather than escalate on schedule

Patients averaging 7 to 9 hours of sleep per night lose 20 to 30 percent more weight on semaglutide compared to those sleeping 5 to 6 hours, even when calories and exercise are identical

However, if there are less than 48 hours left for your next dose, skip the missed dose and go back to your regular dosing schedule

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