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doi: 10.2337/diabetes.51.9.2757

We asked doctors who prescribe GLP-1 medications to break down this trend and explain whether its worth it to consider microdosing a GLP-1 drug

Researchers acknowledged this contributed to increased gastrointestinal symptoms

Such bidirectional interaction between hyperandrogenism and insulin resistance/hyperinsulinemia likely plays a key role in the pathogenesis of PCOS 12,13,14 , since elevated testosterone promotes obesity and insulin resistance/hyperinsulinemia by altering body composition and insulin signaling in skeletal muscle and adipose tissue, while hyperinsulinemia contributes to increase androgen levels via ovarian-dependent mechanisms 5

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