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Results Despite heterogeneity in study designs and populations, a largely consistent association was found between GLP-1RA use and a reduced incidence of glaucoma

Initial research has indicated that low-dose semaglutide injections can reduce alcohol craving and some drinking outcomes, prompting calls for a larger clinical trial to evaluate GLP-1RAs for alcohol use disorder.

While the absolute risk increase was modest, our findings point to an important potential adverse effect that clinicians should consider, especially in patients with predisposing factors for GERD

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