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Abrupt cessation may lead to weight regain (70%-80% of lost weight within one year), rebound hunger, and metabolic changes

Data from randomized controlled trials suggest that withdrawing either glucagon-like peptide-1 (GLP-1) receptor agonists or dual gastric inhibitory polypeptide (GIP)/GLP-1 receptor agonists leads to a substantial regain of lost weight
Quantitative visualization of synchronized insulin secretion from 3D-cultured cells
