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6 Deletion of His 7 resulted in a significant loss of affinity ( K d = 33 nM compared to 0.3 nM of GLP-1), and the activity of the truncated peptide became 82% lower than that of GLP-1

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Remember that GLP-1 drugs slow down digestion

The concordance and heritability of type 2 diabetes in 34,166 twin Pairs from international twin registers: the Discordant Twin (DISCOTWIN) Consortium
