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For people struggling with weight, GLP-1 levels or signaling may be lower, contributing to increased hunger

Some studies have found that GLP-1RAs may play an anti-osteoporotic effect by controlling blood sugar levels, promoting bone formation and inhibiting bone resorption

42,43 Several GLP-1R agonists, including exenatide, liraglutide, and semaglutide, have been used in NASH clinical research

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Benefits for SGLT-2 inhibitors and GLP-1 receptor agonists on the absolute scale were largest for those with heart failure, chronic kidney disease, or those using mineralocorticoid receptor antagonists